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AssigneesMeito Sangyo Kabushiki Kaisha, Otsuka Pharamaceutical Factory, Inc.
InventorsHaruo Machida, Shigeaki Kato, Yuuki Hirata, Mitsuo Aoki, Hideki Kobatake
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The present invention relates to dextran whose boron content is reduced to a value less than 0.30 μg/g (dry basis) calculated on the basis of boron atom, a process for producing the same, and dextran with which a container is filled in a solution state. Dextran of the present invention is obtained by treating a boron-containing dextran with a lower alcohol, and said dextran has such a characteristic that deposition is inhibited or the deposition rate is drastically reduced when using it in the form of a solution. Therefore, an isotonic sodium chloride solution of said dextran is suitably used as substitute plasma or external perfusate in an operation.
A process for producing dextran having a reduced boron content which comprises preparing a solution obtained by contacting a boron-containing dextran as a starting material with a lower alcohol to convert boron in the dextran into a trialkyl borate and;
Dependencies are inferred from the claim text.