36 human secreted proteins
AssigneeHuman Genome Sciences, Inc.
InventorsHenrik S. Olsen, Steven M. Ruben, Craig A. Rosen, Laurie A. Brewer, Reinhard Ebner, Roxanne Duan, Kimberly Florence
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Abstract
The present invention relates to 36 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
Claims42
An isolated protein comprising amino acid residues 23 to 74 of SEQ ID NO:73.
An isolated protein comprising the amino acid sequence of the secreted portion of the polypeptide encoded by the HAMGO32 cDNA contained in ATCC Deposit No. 209626.
An isolated first polypeptide at least 90% identical to a second polypeptide consisting of amino acid residues 23 to 74 of SEQ ID NO:73.
An isolated first polypeptide at least 90% identical to a second polypeptide consisting of the secreted portion of the polypeptide encoded by the HAMGO32 cDNA contained in ATCC Deposit No. 209626.
An isolated first polypeptide at least 90% identical to a second polypeptide consisting of amino acid residues 1 to 74 of SEQ ID NO:73.
An isolated first polypeptide at least 90% identical to a second polypeptide consisting of the complete polypeptide encoded by the HAMGO32 cDNA contained in ATCC Deposit No. 209626.
An isolated protein consisting of at least 30 contiguous amino acid residues of amino acid residues 1 to 74 of SEQ ID NO:73.
An isolated protein consisting of at least 30 contiguous amino acid residues of the complete polypeptide encoded by the HAMGO32 cDNA contained in ATCC Deposit No. 209626.
Dependencies are inferred from the claim text.