Compositions containing a selenium monobromide-oil reaction product and epichlorohydrin and methods of making the same
OwnerElena Avraminventor
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Abstract
A composition of selenium monobromide-oil reaction product including a reaction product of selenium momobromide-in-oil prepared from eleostearic acid and selenium monobromide, which contains at least about 0.1 percent of selenium monobromide and exhibits ultraviolet absorption maxima typical of conjugated trienes and conjugated dienes and pharmnaceutical composition thereof for administration to a subject in a therapeutically effective amount to treat neoplastic conditions such as cancer. Methods of making such compositions are also encompassed, as are methods for treating neoplastic conditions by administering to a subject an effective amount of a selenium monobromide-oil reaction product with epichlorohydrin.
Claims20
A composition comprising a reaction product prepared from an oil containing eleostearic acid, and selenium monobromide, which comprises at least about 0.1 weight percent of reacted selenium monobromide and exhibits ultraviolet absorption maxima typical of conjugated trienes and conjugated dienes.
A process of preparing a reaction product which comprises reacting an eleostearic acid-containing oil and selenium monobromide at a sufficient temperature and for a sufficient time to incorporate at least about 0.1 weight percent of selenium monobromide in the oil.
A pharmaceutical composition for administration to a human subject comprising:
- a reaction product prepared from an oil containing eleostearic acid, and selenium monobromide, which contains at least 0.1 weight percent of reacted selenium monobromide and exhibits ultraviolet absorption maxima typical of conjugated trienes and conjugated dienes and a pharmaceutically acceptable liquid which acts as a carrier.
Dependencies are inferred from the claim text.