Cyclic diamine compound with condensed-ring groups

A pharmaceutical composition comprising as an active ingredient a cyclic diamine compound of formula (1):

• wherein R1 and R2 are individually a hydrogen atom or a methoxy group, provided R1 is a methoxy group when R2 is a hydrogen atom, or R1 is a hydrogen atom when R2 is a methoxy group;
• A is an oxygen atom, a sulfur atom, CH═CH, CH═N or NR3, in which R3 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group;
• B is a nitrogen atom, CH or CR4, in which R4 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group;
• m is 2;
• and n is a number of 1 to 5,
• an acid-addition salt thereof, or a hydrate thereof, and a pharmaceutically acceptable carrier.

A method for treating a disease selected from the group consisting of allergy, asthma, inflammation, rheumatism and arteriosclerosis, which comprises administering to a patient in need thereof a cyclic diamine compound formula (1):

• wherein R1 and R2 are individually a hydrogen atom or a methoxy group, provided R1 is a methoxy group when R2 is a hydrogen atom, or R1 is a hydrogen atom when R2 is a methoxy group;
• A is an oxygen atom, a sulfur atom, CH═CH, CH═N or NR3, in which R3 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group;
• B is a nitrogen atom, CH or CR4, in which R4 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group;
• m is 2;
• and n is a number of 1 to 5,
• an acid-addition salt thereof, or a hydrate thereof.