Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same
AssigneeNippon Zeon Co., Ltd.
InventorsShuji Saitoh, Takashi Okuda
Life of this patent
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Abstract
An avian infectious recombinant herpesvirus is prepared by inserting a foreign gene, in particular a heterologous antigen gene, into an insertion site in an untranslated genetic region in the genome. A chicken vaccine comprising such a recombinant virus is also provided.
Claims25
An avian infectious recombinant herpesvirus comprising a foreign gene inserted into an insertion site in an untranslated genetic region in the genome, wherein said insertion site is selected from the group consisting of sites (1) between UL44 and UL45, and (2) between UL45 and UL46.
An avian infectious recombinant herpesvirus comprising a foreign gene consisting essentially of a gene selected from VP2 of IBDV, HF of NDV and F of NDV inserted into a genetic region that is an untranslated region in the genome selected from UL44-UL45 and UL45-UL46 of HVT.
An avian infectious recombinant herpesvirus selected from HVT and MDV, said herpesvirus comprising a foreign gene inserted into an insertion site in an untranslated genetic region in the genome, wherein said insertion site is selected from the group consisting of sites (1) between UL44 and UL45, and (2) between UL45 and UL46.
Dependencies are inferred from the claim text.