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US 6,632,638 B1Granted
Enhanced solubility of recombinant proteins using Uracil DNA glycosylase inhibitor
AssigneeAmgen Inc.
InventorsMarshall Snavely, Lana Klionsky
Life of this patent
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Abstract
Disclosed are methods for improving the solubility of a protein of interest produced recombinantly by expressing the protein of interest as a fusion protein with Uracil DNA glycosylase inhibitor (UGI).
Claims9
A method of increasing the solubility of a protein of interest produced in a host cell comprising expressing the protein as a fusion protein with Uracil DNA glycosylase inhibitor (UGI).
Dependencies are inferred from the claim text.