Back to results
US 6,632,455 B2Granted
Molecular dispersion composition with enhanced bioavailability
AssigneeSchering Corporation
InventorsSurendra A. Sangekar, Ping I. Lee, Amin A. Nomeir
Life of this patent
Estimating the term…
Abstract
A molecular dispersion composition is disclosed. The molecular dispersion comprises a compound of the formula: molecularly dispersed in a polymer matrix. Also disclosed are solid dosage forms, e.g., tablets and capsules, containing these molecular dispersions.
Claims3
The pharmaceutical composition in a solid dosage form for oral consumption, comprising a compound having the formula I:
- molecularly dispersed in a polymer matrix consisting essentially of polyvinylpyrrolidone, wherein the compound is present in a proportion of form about 15 to 60% by weight, based on the total weight of the pharmaceutical composition, a ratio of the compound to the polymer is from about 1:0.5 to about 1:4, and the solid form pharmaceutical composition has an enhanced bioavailability when orally consumed compared to orally consumed solid form pharmaceutical compositions that comprise the compound having the formula I where it is not molecularly dispersed in the polymer matrix.
Dependencies are inferred from the claim text.