Modulators of methylation for control of bacterial virulence
AssigneeAntiCancer, Inc.
InventorsMingxu Xu, Quinghong Han, Yuying Tan
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Abstract
Compositions and methods which ameliorate the virulence of bacterial infection are described wherein the active ingredient modulates transmethylation reactions in bacterial cells. Particularly useful compounds are inhibitors of S-adenosyl methionine synthetase (SAMS), of S-adenosyl homocysteine hydrolase (SAHH) and of transmethylases.
Claims13
A method for treating a bacterial infection which method comprises administering to a subject in need thereof an amount of methioninase sufficient to treat such infection.
A method for treating a bacterial infection which method comprises identifying a subject afflicted with bacterial infection and administering to said subject in need thereof an effective amount of methioninase sufficient to treat such infection.
A method for treating a bacterial infection which method comprises identifying a subject afflicted with bacterial infection and treating said subject wherein said treating consists of administering to said subject in need thereof an effective amount of methioninase sufficient to treat such infection.
Dependencies are inferred from the claim text.