Back to results
US 6,632,418 B2Granted
Radioligands and their use for identifying potassium channel modulators
AssigneeAbbott Laboratories
InventorsRobert J. Altenbach, Gary A. Rotert, William A. Carroll, Murali Gopalakrishnan, Eduardo Jose Vicente Molinari, Rachel A. Davis-Taber, Victoria Eleanor Sarah Scott
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel radioligands and test methods using those radioligands in screening compounds.
Claims17
A compound of formula (I)
- wherein
- n is an integer of 0-1;
- m is an integer of 1-2;
- provided that when n is 1, then m is 1;
- A is selected from the group consisting of C(O) and S(O)2;
- D is selected from the group consisting of O, S and CR2R3;
- Z is selected from the group consisting of O and S;
- R1 is selected from the group consisting of alkyl, cyano, haloalkoxy, haloalkyl, halogen and nitro;
- and
- R2, R3, R4, R5, R6 and R7 are each independently selected from the group consisting of hydrogen and alkyl;
- provided that when A is S(O)2;
- then D is CR2R3;
- and
- further provided that when D is S;
- then n is 1 and A is C(O).
12 more elements
Dependencies are inferred from the claim text.