Underwater or under-hydrocarbon pelletizing of biologically-active-compound-containing melts
AssigneeBASF SE
InventorsAndreas Ernst, Thomas Kessler, Gunther Berndl
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Abstract
A process for producing pellets comprising biologically active substances in which the biologically active substances are homogeneously dispersed in a matrix based on at least one thermoplastic polymer, which polymer has in aqueous medium a pH-dependent solubility, by homogeneous mixing of the starting materials in the melt and subsequent extrusion and shaping, which comprises the shaping being performed in a cooling medium in which the pellets are not soluble or dispersible.
Claims9
A process for producing pellets comprising biologically active substances in which the biologically active substances are homogeneously dispersed in a matrix based on at least one thermoplastic polymer, which polymer has in aqueous medium a pH-dependent solubility, so that in one pH range it is water insoluble and in a different pH range it is water soluble, by homogeneous mixing of the starting materials in the melt and subsequent extrusion and shaping, which comprises the shaping being performed in a cooling medium, which cooling medium is a liquid hydrocarbon or water containing an acid or base such that the pH is such that the pellets do not dissolve or are not dispersible.
Dependencies are inferred from the claim text.