Apparatus and method for selective reduction of segmental intracellular and extracellular edema
AssigneeTransvivo, Inc.
InventorsReynolds G. Gorsuch, Kris Venkat
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Abstract
Segmental edema is treated by inserting a plasma extraction filter device in a major vein of a body segment or servicing the body segment containing the edemic tissues, and inserting a return catheter in a major artery of the body segment affected or feeding the body segment from which plasma is extracted. Blood plasma and plasma proteins extracted from the edemic body segment through the plasma extraction filter fluids are directed to an ultrafiltration apparatus where plasma water is separated from the plasma proteins. Plasma proteins are returned to the body segment from which the plasma was extracted via the return catheter in the major artery of the subject body segment.
Claims18
A method of treating segmental edema in a patient comprising:
- inserting a plasma extraction device in a major vein proximal to a body segment containing edemic tissue, said plasma extraction device comprising a plasma extraction filter capable of separating plasma including plasma proteins from blood in-vivo within said vein and a plasma extraction catheter for directing separated plasma from the plasma extraction filter to an ultrafiltration apparatus;
- inserting a return catheter in a major artery of the body segment from which the plasma is extracted;
- separating and extracting plasma and plasma proteins from blood in the major vein through said plasma extraction filter;
- directing the extracted plasma through the plasma extraction catheter to an ultrafiltration apparatus and separating plasma water from plasma proteins therein, and collecting and/or discarding the separated plasma water;
- and
- directing plasma proteins via the return catheter to the major artery of the body segment of the patient from which the plasma is extracted.
The method of claim 1, 23 or 4 comprising pumping plasma water from the ultrafiltration apparatus to a collection container.
A method of treating segmental edema in a patent comprising:
- inserting a plasma water extraction device in a major vein proximal to a body segment containing edemic tissue, said plasma water extraction device comprising an ultrafiltration membrane capable of separating plasma water from blood and plasma protein in-vivo within said vein and a plasma water extraction catheter for directing separated plasma water from the plasma water extraction membrane;
- inserting a return catheter in a major artery of the body segment from which the plasma water is extracted;
- separating plasma water from blood in-vivo in the major vein through said ultrafiltration membrane and directing the separated plasma water from the vein via the plasma water extraction catheter to a plasma water container;
- and
- directing plasma protein via the return catheter to the major artery of the body segment of the patient from which the plasma water is extracted.
Dependencies are inferred from the claim text.