US 6,626,950 B2 · Composite scaffold with post anchor for the repair and regeneration of tissue

Abstract

A prosthetic implant having a tissue scaffold and a fixation device with a scaffold support and an anchoring post. The anchoring post extends from a surface of the scaffold support at a selected angle with the scaffold support embedded within the scaffold. The scaffold has a porous ceramic phase and a porous polymer phase. The polymer is foamed while in solution that is infused in the pores of the ceramic to create a interphase junction of interlocked porous materials and embedding the scaffold support portion of the fixation device. The preferred method for foaming is by lyophilization. The scaffold may be infused or coated with a variety of bioactive materials to induce ingrowth or to release a medicament. The mutilayered porous scaffold can mimic the morphology of an injured tissue junction with a gradient morphology and cell composition.

Claims24

Dependent claims

A prosthetic implant, comprising:

a composite tissue scaffold having a ceramic layer with a first plurality of pores and a polymer layer with a second plurality of pores, said polymer attached to said ceramic at an interphase region, said polymer infused at least partially into said first plurality of pores in said interphase region at least one of said polymer layer and said ceramic layer being biodegradable;
and
a fixation device with a scaffold support and an anchoring post, said anchoring post extending from a surface of said scaffold support at a selected angle, said anchoring post insertable into a receptacle formed in tissue, said scaffold support embedded within said scaffold.

Dependencies are inferred from the claim text.

Composite scaffold with post anchor for the repair and regeneration of tissue

Life of this patent

Composite scaffold with post anchor for the repair and regeneration of tissue

Life of this patent

Abstract

Claims24