Cysteine/glycine rich peptides
AssigneeCampina Melkunie B.V.
InventorsLeon Franciscus Mallee, Ram Nimmagudda, Johannes Wilhelmus L. Boumans
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AssigneeCampina Melkunie B.V.
InventorsLeon Franciscus Mallee, Ram Nimmagudda, Johannes Wilhelmus L. Boumans
Estimating the term…
Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of: a) cleaving the proteins of the protein source into peptides; b) digesting the peptides obtained in step a) by an exopeptidase, the action of which is at least attenuated at the position of a cysteine in the peptide, therewith forming digested peptides having a terminal cysteine; c) purifying the digested peptides, and the use of the preparation as active component in a medicament, especially for the treatment of conditions mediated by oxidative damage and for the elevation of cellular glutathion levels in the human or animal body.
A method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising one or more cysteine-containing proteins, comprising:
A method for the preparation of a mixture of peptides having a total cysteine and glycine content of 7-20 w/w % from a protein source, comprising one or more cysteine-containing and glycine-containing proteins, comprising:
A preparation comprising a mixture of cysteine-rich peptides, which comprise 7-20% w/w cysteine, wherein said peptides have a molecular weight of 5000 Da or more.
A preparation comprising a mixture of cysteine-rich peptides, which comprise 7-20 w/w % cysteine, wherein at least 80% of the peptides comprise a terminal cysteine, terminal glycine, or a combination of both.
A food comprising a preparation comprising a mixture of cysteine-rich peptides, which comprise 7-20 w/w % cysteine.
A pharmaceutical composition or medicament comprising a preparation comprising a mixture of cysteine-rich peptides, which comprise 7-20 w/w % cysteine.
A preparation comprising a mixture of cysteine- and glycine-rich peptides, which comprise 7-20% w/w cysteine and glycine, wherein said peptides have a molecular weight of 5000 Da or more.
A preparation comprising a mixture of cysteine- and glycine-rich peptides, which comprise 7-20 w/w % cysteine and glycine, wherein at least 80% of the peptides comprise a terminal cysteine, terminal glycine or a combination of both.
A food comprising a preparation that comprises a mixture of cysteine and glycine-rich peptides, which corn rise 7-20 w/w % cysteine and glycose.
A pharmaceutical composition or medicament comprising a preparation comprising a mixture of cysteine- and glycine-rich peptides, which comprise 7-20 w/w % cysteine and glycine.
Dependencies are inferred from the claim text.