Back to results
US 6,617,459 B2Granted
Azabicyclo derivatives and their use
AssigneeNeuroSearch A/S
InventorsDan Peters, Jørgen Scheel-Krüger, Elsebet Østergaard Nielsen
Life of this patent
Estimating the term…
Abstract
The present invention relates to 8-azabicyclo[3.2.1]oct-2-ene derivatives in their labelled form. Furthermore, the present invention relates to the use of said derivatives in their labelled or unlabelled form in diagnostic methods, in particular for in vivo receptor imaging (neuroimaging).
Claims5
A chemical compound represented by the general formula
- wherein
- n is 0 or 1;
- R is hydrogen alkyl, haloalkyl, alkenyl, haloalkenyl alkynyl, haloalkynyl, cycloalkyl, cycloalkyalkyl, or 2-hydroxyethyl, alkylamino, alkenylthio, alkynylthio or a leaving group;
- and
- R4 is phenyl substituted one or more times with —O—R″, wherein (R″) represents haloalkyl,
- or any enantiomer of a compound of formula (I), or any mixture thereof, or any radioactively labelled compound of formula (I) or a pharmaceutically acceptable salt thereof.
3 more elements
Dependencies are inferred from the claim text.