Ataxin-2 binding proteins
AssigneeCedars-Sinai Medical Center
InventorsStefan M. Pulst, Hiroki Shibata
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Abstract
In accordance with the present invention, there are provided novel isolated nucleic acids encoding ataxin-2-binding proteins (A2BPs), functional fragments thereof, vectors containing invention nucleic acids and recombinant cells transformed therewith, antisense-nucleic acids thereto. Also provided are novel isolated ataxin-2-binding proteins (A2BPs) having ability to bind to ataxin-2, methods for expression of A2BP, transgenic non-human mammals that express invention A2BP, anti-A2BP antibodies, and methods related thereto.
Claims6
An isolated ataxin-2 binding protein (A2BP) characterized by having an ability to bind to ataxin-2, wherein the amino acid sequence of said protein comprises substantially the same sequence as SEQ ID NO:2.
An isolated ataxin-2 binding protein (A2BP) characterized by having an ability to bind to ataxin-2, wherein said protein is encoded by a nucleotide sequence comprising substantially the same nucleotide sequence as nucleotides 987-1979 of SEQ ID NO:1.
Dependencies are inferred from the claim text.