2-arylquinoline derivatives, preparation and therapeutic use thereof

A compound of formula (I)

• wherein:
• A represents a hydrogen atom, a hydroxyl, a C1-3 alkoxy group, a hydroxy(C1-6 alkyl) group, a (C1-3 alkoxy)(C1-3 alkyl) group, a thiol, (C1-6 alkyl)sulfanyl or a halogen;
• B and D represent, independently of one another, a hydrogen atom, a C1-6 alkyl group, a fluoro(C1-6 alkyl) group or a perfluoro(C1-2 alkyl) group or B and D together from an oxo;
• R1 represents a phenyl, a naphthyl or a heteroaryl comprising 4 or 5 carbon atoms and, as heteroatom, an oxygen, a sulfur or a nitrogen;
• it being possible for the phenyl, the naphthyl or the heteroaryl to be substituted by one, two or three substituents chosen from the group consisting of a halogen, a hydroxyl, a nitro, an amino, an azido, a C1-6 alkyl group, a hydroxy(C1-6 alkyl) group, a (C1-6 alkyl)carbonyl group, a (C1-6 alkyl)amino group, a di(C1-6 alkyl)amino group, a fluoro(C1-6 alkyl) group, a perfluoro(C1-2 alkyl) group, a C1-6 alkoxy group, a phenyl, a benzyl, and a benzyloxy;
• R2 and R3 represent, independently of one another, a hydrogen atom, a halogen or a C1-6 alkyl group,
• R4 represents a hydrogen atom, a hydroxyl or a halogen, and
• R5 and R6 represent, independently of one another, a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, a C3-6 cycloalkyl group, a C3-6 cycloalkenyl group, a fluoro(C1-6 alkyl) group or a perfluoro(C1-2 alkyl) group or R5 and R6 together form a C2-6 alkylene chain or a C3-6 alkenylene chain, to give, with the nitrogen to which they are attached, a heterocycle, this heterocycle optionally being substituted by a C1-4 alkyl group;
• or an acid-addition salt thereof.