Methods of use for 2-deoxy ecdysterone
AssigneeCouncil of Science and Industrial Research
InventorsCynthia Olimpia Lydia Gonsalves, Perunninakulath Parameswaran Subrayan, Chandrakant Govind Naik, Chittur Thelakkat Achuthankutty
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Abstract
The invention provides a process for the isolation of 2-deoxy ecdysterone from Zoanthus sp process comprising the steps (a) preparing crude methanol extract of Zoanthus sp., (b) subjecting the crude methanol extract to fractionation using petroleum ether, ethyl acetate, chloroform, n-butanol and mixtures thereof to yield a fraction, (c) subjecting the active fraction to flash chromatography over silica gel to obtain partially purified active compound, and (d) subjecting the active subfraction obtained from step (c) above to gel permeation chromatography to obtain the active pure compound.
Claims13
A method of inducing uterus contractions in a mammal, comprising:
- administering to said mammal an effective amount of 2-deoxy ecdysterone prepared by a process comprising isolating and purifying 2-deoxy ecdysterone from Zoanthus sp. thereby inducing uterus contractions.
Dependencies are inferred from the claim text.