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US 6,617,318 B1Granted
Methods of preparing substituted tetracyclines with transition metal-based chemistries
AssigneeTrustees of Tufts College
InventorsMark L. Nelson, Glen Rennie, Darrell J. Koza
Life of this patent
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Abstract
The present invention relates to 7-phenyl substituted tetracycline derivatives and compositions thereof.
Claims25
A 7-substituted tetracycline analog, wherein said substituent at the 7 position is connected with a —C—C— linkage, and wherein said substituent is substituted or unsubstituted phenyl.
A 7-substituted tetracycline analog, wherein said analog is 7-4′-Cl-phenyl sancycline.
A 7-substituted tetracycline analog, wherein said analog is 7-(4-fluorophenyl)sancycline.
A 7-substituted tetracycline analog, wherein said analog is 7-(4-nitrophenyl)sancycline.
Dependencies are inferred from the claim text.