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US 6,617,314 B2Granted
Injectable formulations of avermectins and milbemycins
AssigneeBayer Aktiengesellschaft
InventorsMichael Grosse-Bley, Richard Kujanek
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Abstract
The present application relates to injection formulations of avermectins and milbemycins based on a solvent mixture comprising sesame oil, medium-chain triglycerides, glycol esters or fatty acid esters and a further solvent from the group consisting of mono- or polyhydric aliphatic or aromatic alcohols and their derivatives (e.g. cyclic carbonates; acetates; acetals; ketals) or castor oil.
Claims5
An injectible formulation comprising:
- 1. avermectin or milbemycin 0.2 to 5% m/v;
- 2. sesame oil 60 to 90% v/v;
- 3. 10 to 30% by volume of medium-chain triglycerides or glycol esters or fatty acid esters;
- 4. 1 to 20% co-solvent from the group consisting of mono- or polyhydric aliphatic or aromatic alcohols and their derivatives selected from the group consisting of cyclic carbonates, acetates, acetals and ketals, and castor oil;
- 5. optionally auxiliaries.
2 more elements
Dependencies are inferred from the claim text.