Glucopyranoside and process of isolation thereof from pterocarpus marsupium pharmaceutical composition containing the same and use thereof
AssigneeCouncil of Scientific and Industrial Research
InventorsRakesh Maurya, Sukhdev Swami Handa, Rajinder Singh
Life of this patent
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Abstract
A novel glucopyranoside, 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H) benzofuran-7-C-β-D-glucopyranoside of the formula 1 isolated from Pterocarpus marsupium and to a process for the isolation thereof is disclosed. The invention also relates to a pharmaceutical composition containing 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H)benzofuran-7-C-β-D-glucopyranoside and to method for the treatment of diabetes using said compound.
Claims10
A novel glucopyranoside 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H)benzofuran-7-C-β-D-glucopyranoside of the formula 1
Process for the isolation of 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H)benzofuran-7-C-β-D-glucopyranoside of the formula 1
- which comprises:
- (a) powdering the heartwood of the plant Pterocarpus marsupium,
- (b) extracting the powdered plant material with a protic solvent,
- (c) concentrating the extract to minimum volume and partitioning with different organic solvents of increasing polarity to remove non-polar components, extracting the aqueous layer with polar solvent, removing the solvent to get the residue,
- (d) isolating the 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H)benzofuran-7-C-β-D-glucopyranoside from the residue.
Pharmaceutical composition containing a pharmaceutically effective amount of 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H)benzofuran-7-C-β-D-glucopyranoside of formula 1 in a pharmaceutically acceptable carrier.
Method for the treatment of diabetes comprising administering a pharmaceutically effective amount of 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H)benzofuran-7-C-β-D-glucopyranoside to a patient.
Dependencies are inferred from the claim text.