Vasoactive amine binding molecules

A vasoactive amine binding protein (VABP) that binds to vasoactive amines with a dissociation constant of less than 10−7 M, has a sequence homology to the VABP clones male specific histamine binding protein 1 (MS-HBP1) (SEQ ID NO:20), female specific histamine binding protein 1 (FS-HBP1) (SEQ ID NO:

• 16), female specific histamine binding protein 2 (FS-HBP2) (SEQ ID NO:
• 18), and Dermacenter reticularis 6 (D.RET6) (SEQ ID NO:
• 22), such that 40% or more of the amino acids of said VABP clones that are completely conserved as identical residues when said VABP clones are in alignment with each other, are still completely conserved when said VABP is included in said alignment;
• and that contains a sequence motif selected from the group consisting of the motifs (Asp or Glu)-Ala-Trp-(Lys or Arg) (SEQ ID NO:
• 23) and (Tyr or Cys)-(Glu or Asp)-(Leu or Ile)-Trp (SEQ ID NO:
• 24).