Method of making chewing gum containing colloidal bismuth subcitrate
AssigneeJosman Laboratories, Inc.
InventorNarayan K. Athanikar
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Abstract
The invention provides a method of making a chewing gum composition containing a water soluble bulk portion, a water insoluble chewing gum base portion, a flavoring agent, and bismuth-containing compounds. The invention provides a method of making a bismuth-containing gum which when chewed multiple times per day, over the period of two weeks, is effective in reducing peptic ulcers by eradicating H. pylori. The chewing gum is also effective in eliminating forms of halitosis. The chewing gum does not have undesirable side effects, such as unpleasant taste and poor chewing characteristics.
Claims18
A method of making a chewing gum for treatment of H. pylori in the oral cavity and gastric mucosa, the method comprising:
- a) providing a chewing gum base,
- b) providing a non-H2 antagonist bismuth compound, which is therapeutically effective against H. pylori in the oral cavity,
- c) mixing the chewing base and the non-H2 antagonist bismuth compound in sufficient proportions such that the amount of the non-H2 antagonist bismuth compound in a suitable serving size of chewing gum is therapeutically effective, and
- d) shaping the mixture into a desired product form;
- wherein the non-H2 antagonist bismuth compound is selected from the group consisting of colloidal bismuth subcitrate, bismuth citrate, bismuth subcitrate, bismuth salicylate, bismuth subsalicylate, bismuth subnitrate, bismuth subcarbonate, bismuth tartrate, bismuth subgallate, bismuth aluminate, bismuth ascorbyl sulfate, bismuth sucrose sulfate, and combinations thereof.
Dependencies are inferred from the claim text.