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US 6,616,699 B2Granted
Foam-type vascular prosthesis with well-defined angio-permissive open porosity
OwnerPeter Paul Zilla, Deon Bezuidenhoutinventors
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Abstract
A vascular prosthesis is constructed from a well-defined pore structure to allow uninterrupted ingrowth of connective tissue into a wall of the prosthesis. Several different methods can be used to produce the prosthesis, including a vacuum impregnation technique, a paste molding technique, a paste extrusion technique, a dip coating technique, and a melt extrusion technique. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.
Claims25
A method of making a prosthesis comprising the steps of:
- providing at least one cylindrical mold in a casting device, with a central rod centrally positioned within the mold;
- filling an annulus of the at least one mold with extractable filler particles;
- injecting a graft material solution into the annulus, such that the graft material solution permeates spaces between the filler particles in the at least one mold;
- precipitating graft material from the graft material solution;
- removing the central rod from the at least one mold;
- removing the graft material from the at least one mold;
- and
- extracting the filler particles from the graft material.
5 more elements
Dependencies are inferred from the claim text.