Systems and method for controlling renovascular perfusion
AssigneeCVRx, Inc.
InventorRobert S. Kieval
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Abstract
Devices, systems and methods by which the real or apparent renovascular perfusion and intrarenal pressure may be selectively and controllably increased. By selectively and controllably increasing renovascular perfusion and interstitial hydrostatic pressure when the heart is unable to pump sufficient blood or when renal perfusion is suboptimal, the present invention reduces or reverses neurohormonal activation and fluid retention, and thereby minimizes their deleterious effects on the heart, vasculature, kidneys and other body systems.
Claims30
A method of treating a patient comprising the steps of:
- providing a blood perfusion modification device;
- positioning the blood perfusion modification device in the patient's renovascular circulation or immediately adjacent thereto;
- providing a sensor;
- positioning the sensor in a renal artery or upstream thereof to generate a signal indicative of a need to modify renal perfusion;
- and
- activating, deactivating or otherwise modifying the blood perfusion modification device as a function of the sensor signal to cause an increase in renal perfusion.
A method of treating a patient having a clinical condition, the method comprising the steps of:
- diagnosing or monitoring the clinical condition or a sign thereof;
- providing a blood perfusion modification device;
- positioning the blood perfusion modification device in the patient's renovascular circulation or immediately adjacent thereto;
- and
- activating, deactivating or otherwise modifying the blood perfusion modification device to cause an increase in renal perfusion to thereby treat the clinical condition.
A method of treating a patient comprising the steps of:
- providing a blood perfusion modification device;
- positioning the blood perfusion modification device in the patient's renovascular circulation or immediately adjacent thereto;
- providing a sensor;
- positioning the sensor in a renal artery or upstream thereof to generate a signal indicative of a need to modify renal perfusion;
- and
- activating, deactivating or otherwise modifying the blood perfusion modification device as a function of the sensor signal to cause an increase in renal perfusion,
- wherein the sensor generates a signal indicative of urine production, and wherein the modification device is activated, deactivated or otherwise modified when the urine production falls below or rises above a predetermined threshold value.
Dependencies are inferred from the claim text.