US 6,610,886 B2 · Intermediate for preparing midodrine

Abstract

The invention provides a process for the preparation of 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide of the formula 1 by hydrogenolysis of substituted 2-dibenzylamino-N-[2-(2′,5′-dimethoxyphenyl)-2-hydroxy-ethyl]acetamide having the formula (5), wherein Ar and Ar′ are aryl groups.

Claims1

Dependent claims

2-dibenzylamino-N-[2-(2′,5′-dimethoxyphenyl)-2-hydroxyethyl]-acetamide having the formula (7)

Dependencies are inferred from the claim text.

Facts

Application

10/206,968Filed 30 Jul 2002 · division

Priority

IL 14165526 Feb 2001

Published

US 2002/0128511 A119 Dec 2002

Granted

26 Aug 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification3 codes

C07C 237/08
The carbon skeleton being acyclic and saturated: having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon…
C07C 231/12
Preparation of carboxylic acid amides: by reactions not involving the formation of carboxamide groups
C07C
Acyclic or carbocyclic compounds

Intermediate for preparing midodrine

Life of this patent

Abstract

Claims1

Intermediate for preparing midodrine

Life of this patent

Abstract

Claims1