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US 6,610,854 B2Granted
Substituted condensation products of N-benzyl-3-indenylacentamides with heterocyclic aldehydes for neoplasia
AssigneesCell Pathways, Inc., University of Arizona
InventorsGerhard J. Sperl, Paul Gross, Klaus Brendel, Gary A. Piazza, Rifat Pamukcu
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Abstract
Substituted condensation products of N-benzyl-3-indenylacetamides with heterocyclic aldehydes are useful for inducing or promoting apotosis and for arresting uncontrolled neoplastic cell proliferation, and are specifically useful in the arresting and treatment of neoplasias, including precancerous and cancerous lesions.
Claims2
(Z)-5-Fluoro-2-methyl-(4-pyridylidene)-3-(N-benzyl)indenylacetamide.
A method of preparing (Z)-5-fluoro-2-methyl-(4-pyridylidene)-3-(N-benzyl)indenylacetamide hydrochloride, comprising:
- reacting (Z)-5-Fluoro-2-methyl-(4-pyridylidene)-3-(N-benzyl)indenylacetamide with hydrochloric acid.
Dependencies are inferred from the claim text.