Treatment of osteoarthritis
AssigneeLaboratoires Negma
InventorsSuzy Charbit, Francois Schutze, Alain Taccoen, Jean-Pierre Pelletier, Diego Provvedini
Life of this patent
Estimating the term…
Abstract
A method of treating osteoarthritis, which is effective not only at targeting the symptoms of the disease, but also in interrupting, preventing, and controlling cartilage destruction, to thereby favorably alter the course of the disease, comprising the administration of an effective amount of rhein or a rhein derivative, preferably diacerein, either alone or in combination with at least one member selected from the group consisting of analgesics, antipyretics, cortico-steroids, anti-inflammatory agents, cyclooxygenase-2 inhibitors, and inflammatory cytokine inhibitors, to a subject in need of such treatment.
Claims18
A method for treating osteoarthritis by delaying the progression of the destruction of joint cartilage comprising the administration of an effective amount of a member selected from a first group consisting of rhein and esters of rhein as the active agent.
A method of concurrently treating the symptoms of arthritis and delaying the progression of arthritis by controlling the destruction of joint cartilage, comprising administering an effective amount of a member selected from the group consisting of rhein and esters of rhein.
A method of treating osteoarthritis by delaying the progression of the destruction of joint cartilage and relieving symptomatic discomfort, comprising the administration of an effective amount of a member selected from a first group consisting of rhein and esters of rhein;
- and an effective amount of at least one member selected from a second group consisting of analgesics, antipyretics, corticosteroids, anti-inflammatory agents, cyclooxygenase-2-inhibitors, and cytokine inhibitors.
Dependencies are inferred from the claim text.