Benzofuranylsulfonates

Benzofuranylsulfonates of the general formula (I)

• in which
• A represents hydrogen, straight-chain or branched acyl or alkoxycarbonyl, each having up to 6 carbon atoms, halogen, carboxyl, cyano, nitro, hydroxyl, trifuoromethyl or trifuoromethoxy, or straight-chain or branched alkyl having up to 6 carbon atoms, which is optionally substituted by carboxyl, alkoxy or alkoxycarbonyl each having up to 4 carbon atoms, phenoxy or benzoyl,
• R1 represents hydrogen, straight-chain or branched alkyl having up to 4 carbon atoms, an amino protecting group or a group of the formula —CO—R5
• in which
• R5 denotes straight chain or branched alkoxy having up to 4 carbon atoms,
• R2 and R3 are identical or different and represent hydrogen, cycloalkyl having up to 6 carbon atoms, straight chain or branched alkyl, alkoxycarbonyl or alkenyl each having up to 8 carbon atoms,
• or
• R2 and R3 together with the nitrogen atom form a 5- to 7-membered saturated heterocycle optionally having a further O atom,
• R4 represents aryl having 6 to 10 carbon atoms or represents a 5 to 7 membered, aromatic, saturated or unsaturated heterocycle, which can contain up to 3 heteroatoms selected from oxygen, sulphur and nitrogen atoms, or a residue of a formula —NR6,
• wherein
• R6 denotes hydrogen or straight-chain or branched alkyl or alkoxycarbonyl each having up to 6 carbon atoms,
• and to which further a benzene ring can be fused and wherein aryl and the heterocycle are optionally monosubstituted to trisubstituted by identical or different substituents from the series hydroxyl, halogen, nitro, 1H-tetrazolyl, pyridyl, trifluoromethyl, trifluromethoxy, difluoromethyl, difluoromethoxy, cyano, carboxy, straight-chain or branched alkoxy, alkoxycarbonyl or acyl each having up to 6 carbon atoms or by straight-chain or branched alkyl having up to 5 carbon atoms, which is optionally substituted by carboxyl or straight-chain or branched alkoxycarbonyl having up to 4 carbon atoms or by a group of formula —NR7R8, —SR9, —(NH)a—SO2R10 or —O—SO2R11,
• in which
• R7 and R8 are identical or different and denote hydrogen or a straight-chain or branched alkyl having up to 4 carbon atoms,
• or
• R7 denotes hydrogen
• and
• R8 denotes straight-chain or branched acyl having up to 6 carbon atoms
• R9 denotes hydrogen or straight-chain or branched alkyl having up to 4 carbon atoms,
• a denotes a number 0 or 1,
• R10 and R11 are identical or different and represent straight-chain or branched alkyl having up to 6 carbon atoms, benzyl or phenyl, which are optionally substituted by trifluoromethyl, halogen or straight-chain or branched alkyl having up to 4 carbon atoms,
• L represents an oxygen or sulfur atom,
• D represents a residue of a formula
• or aryl having 6 to 10 carbon atoms or a 5 to 7-membered aromatic, saturated or unsaturated heterocycle having up to 3 heteroatoms from the series N, S and O and to which a phenyl ring can be fused, wherein all abovementioned residues and ring systems are optionally monosubstituted to trisubstituted by at least one substituent selected from halogen, carboxyl, straight-chain or branched alkyl or alkoxycarbonyl each having up to 6 carbon atoms, pyridyl, and groups having the formulae —NR12—E—R13, —NR14—CO—NR15R16, —NR17—SO2—NR18R19, —SO2R20 and —(SO2)b—NR21R22,
• wherein
• b denotes a number 0 or 1,
• E denotes a residue of formula SO2 or CO,
• R12, R14, R15, R16, R17, R18, R19, R21 and R22 are identical or different and denote hydrogen, phenyl or straight-chain or branched alkyl having up to 6 carbon atoms,
• R13 denotes straight-chain or branched alkyl or alkoxy each having up to 6 carbon atoms,
• R20 denotes benzyl, phenyl, pyridyl or straight-chain or branched alkyl having up to 6 carbon atoms,
• or
• D represents straight-chain or branched alkyl or alkenyl having up to 8 carbon atoms, which are monosubstituted to trisubstituted by at least one substituent selected from halogen, aryl having 6 to 10 carbon atoms, a 5 to 7-membered saturated or unsaturated heterocycle having up to 3 heteroatoms from the series N, S and O and to which a phenyl ring can be fused, a group of formula —NR23R24,
• and
• wherein
• R23 and R24 have the abovementioned meaning of R15 and R16 and are identical or different.
• wherein the abovementioned ring systems are optionally substituted by halogen,
• and in the case that
• R4 does not represent phenyl or substituted phenyl,
• D in addition can represent benzyl or straight-chain or branched alkyl having up to 5 carbon atoms,
• or
• D optionally represents a residue of a formula —NR25R26
• wherein
• R25 and R26 have the abovementioned meaning of R21 and R22 and are identical or different,
• and salts thereof.