Safe attenuated bovine viral diarrhea viruses for use in pregnant cows
AssigneeBoehringer Ingelheim Vetmedica GmbH
InventorsKnut Elbers, Gregor Meyers
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Abstract
This invention relates to the use of specifically attenuated live BVD (bovine viral diarrhea) viruses for the preparation of a vaccine for use in the prevention and/or treatment of BVDV infections in breeding stocks of cattle, pregnant cows and for fetal protection in pregnant cows.
Claims16
A method of preventing fetal infection with bovine viral diarrhea virus (BVDV), pregnant cow infection with BVDV, or cow-to-calf transmission of BVDV, the method comprising administering to a pregnant cow a vaccine comprising a live attenuated BVDV, wherein the RNase activity residing in the glycoprotein ERNS of the live attenuated BVDV is inactivated.
Dependencies are inferred from the claim text.