Process for the preparation of (2R)-2-propyloctanoic acid
AssigneesOno Pharmaceutical Co., Ltd., Tokyo Kasei Kogyo Co., Ltd.
InventorsNorikazu Toda, Kaoru Yamaguchi, Youichi Iguchi
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Abstract
A process for the preparation of (2R)-2-propyloctanoic acid which is characterized by subjecting (2S)-2-(2-propynyl)octanoic acid or (2S)-2-(2-propenyl)octanoic acid to reduction using platinum on carbon. This process gives (2R)-2-propyloctanoic acid having high optical purity without isomerization.
Claims8
A process for the preparation of (2R)-2-propyloctanoic acid which is characterized by subjecting (2S)-2-(2-propynyl)octanoic acid or (2S)-2-(2-propenyl)octanoic acid to reduction using platinum on carbon.
(2R)-2-propyloctanoic acid having optical purity greater than 97.14% e.e.
Dependencies are inferred from the claim text.