5-hydroxytryptophol (5-HTOL) derivatives, antibodies, immunoassays and detection of recent alcohol consumption
AssigneeAlco Dia A.B.
InventorsRagnhild Brandt, Olof Beck, Anders Helander, Rose-Marie Jonsson, Eric Unger, Stefan Borg, Eva Akerblom
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Abstract
Antibody specific for a 5-HTOL compound. A glucuronide with 5-hydroxytryptophol (5-HTOL) characterized in that it comprises the structure of the β-glucuronide between the 5-hydroxy group of 5-HTOL and D-glucopyranosiduronic acid. An immunoassay and a diagnostic method utilizing the ummunoassay wherein a 5-hydroxytryptophol (5-HTOL) compound is determined by the use of an antibody specific for a 5-HTOL compound is used.
Claims3
An antibody specific for a 5-HTOL compound wherein said 5-HTOL compound is selected from the group consisting of 5-hydroxytryptophol, a glucuronide conjugate of 5-hydroxytryptophol, and a sulphate conjugate of 5-hydroxytryptophol.
Dependencies are inferred from the claim text.