Syndiotactic poly(lactic acid)
AssigneeCornell Research Foundation, Inc.
InventorGeoffrey W. Coates
Life of this patent
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Abstract
Syndiotactic poly(lactic acid) is formed by polymerization involving a cleavage of the same oxygen-acyl bond in a series of meso-lactide molecules to form polymer containing a series of units with stereocenters wherein adjacent stereocenters are of the opposite stereochemistry. The mechanism is catalyzed by chiral metal alkoxides that afford stereocontrol such as those formed by reacting or the opposite enantiomer with Al(OR)3 where R is straight chain or branched alkyl containing 1 to 20 carbon atoms, e.g., methyl or isopropyl, in solvent, with subsequent evaporation of solvent in vacuo.
Claims9
Syndiotactic poly(lactic acid) comprising the structure:
- where n ranges from 20 to 5,000 and containing enantiotopic selectivity greater than 60%.
A process for preparing syndiotactic poly(lactic acid) comprising the structure:
- where n ranges from 20 to 5,000 and containing enantiotopic selectivity greater than 50%, said process comprising ring opening polymerization of meso-lactide in the presence of a chiral metal alkoxide catalyst, where the same oxygen-acyl bond in a series of meso-lactide molecules is cleaved, whereby a polymer is formed containing a series of units containing stereocenters where adjacent stereocenters are of opposite stereochemistry.
Dependencies are inferred from the claim text.