Use of metalloproteinase inhibitors in the treatment and prevention of pulmonary emphysema
AssigneeThe Trustees of Columbia University in the City of New York
InventorsJeanine D'Armiento, Kiran Chada
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Abstract
The invention provides a use of a metalloproteinase inhibitor for the preparation of a pharmaceutical composition for treating human pulmonary emphysema which comprises admixing the metalloproteinase inhibitor in an amount effective to treat human pulmonary emphysema and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition which comprises a metalloproteinase inhibitor in an amount effective to treat human pulmonary emphysema and a pharmaceutically acceptable carrier.
Claims5
A method of treating human pulmonary emphysema in a subject in need of such treatment comprising administering to the subject an amount of a matrix metalloproteinase inhibitor effective to treat the human pulmonary emphysema and a pharmaceutically acceptable carrier, thereby treating the human pulmonary emphysema in the subject, wherein the matrix metalloproteinase inhibitor is a hydroxamic acid.
Dependencies are inferred from the claim text.