Sulfonylbenzene compounds as anti-inflammatory/analgesic agents

A compound of the formula:

• or its pharmaceutically acceptable salt thereof, wherein
• A is partially unsaturated or unsaturated five membered heterocyclic, or partially unsaturated or unsaturated five membered carbocyclic, wherein the 4-(sulfonyl)phenyl and the 4-substituted phenyl in the formula (I) are attached to ring atoms of Ring A adjacent to each other;
• R1 is aryl and the aryl being optionally substituted by one to four substituents selected from halo, C1-4 alkyl, halo-substituted C1-4 alkyl, C1-4 alkoxy, C1-4 alkyl carbonyl, hydroxy, nitro, cyano and amino;
• R2 is C1-4 alkyl, halo-substituted C1-4 alkyl, C1-4 alkylamino, C1-4 dialkylamino or amino;
• R3, R4 and R5 are independently hydrogen, halo, C1-4 alkyl, halo-substituted C1-4 alkyl, C2-5 alkenyl, C2-5 alkynyl, C1-4 alkoxy, hydroxy-C1-4 alkyl, C1-4 alkoxy C1-4 alkyl, C1-4 alkanoyl, cyano, nitro, cyano C1-4 alkyl, carboxy, C1-4 alkoxycarbonyl, aminocarbonyl, N—C1-4 alkylaminocarbonyl, N,N-di C1-4 alkylaminocarbonyl, N-arylaminocarbonyl, N,N-diarylaminocarbonyl, N—C1-4 alkyl-N-arylaminocarbonyl, aryl, aryloxy, aryloxy-C1-4 alkyl, heteroaryl, heteroaryloxy, heteroaryloxy-C1-4 alkyl, morphonlino-carbonyl, C1-4 alkoxyaminocarbonyl or C1-4 alkyl-carbonylamino;
• or two or R3, R4 and R5 are taken together with atoms to which they are attached and form a 4-7 membered ring;
• R6 and R7 are independently hydrogen, halo, C1-4 alkyl, halo-substituted C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylamino, N,N-di C1-4 alkylamino, hydroxyl-C1-4 alkyl, C1-4 alkoxy-C1-4 alkyl, C1-4 alkyl-C1-4 alkoxy, C1-4 alkylamino-C1-4 alkyl, hydroxy, amino C1-4 alkyl and N,N-di C1-4 alkylamino-C1-4 alkyl;
• and
• m and n are independently 1, 2, 3, or 4;
• with the proviso that if A is pyrazolyl, R2 is amino, R3 and R4 are hydrogen, and R5 is halo-substituted C1-4 alkyl, R1 is not unsubstituted phenyl.