Back to results
US 6,608,064 B2Granted
Pharmaceutical agents for the treatment of Parkinson's disease, ADHD and microadenomas
AssigneePfizer Inc.
InventorsStafford McLean, Stevin H. Zorn, Elisa R. Jackson
Life of this patent
Estimating the term…
Abstract
The present invention is directed to the use of certain pyrido[1,2-a]-pyrazine derivatives, also described as bis-azabicyclic compounds and defined by the formula (I) herein, in the treatment of Parkinson's disease, attention deficit hyperactivity disorder and microadenomas in mammals, and to related compositions.
Claims4
A pharmaceutical composition for treating Parkinson's disease in a mammal, comprising:
- (a) a D2 receptor agonizing agent, or a pharmaceutically acceptable salt thereof;
- (b) a 5HT1A receptor agonizing agent, or a pharmaceutically acceptable salt thereof;
- and (c) a pharmaceutically acceptable carrier;
- wherein the foregoing two active agents are present in the composition in amounts such that the combination of such agents is effective in treating Parkinson's disease.
1 more element
A pharmaceutical composition for treating ADHD in a mammal, comprising:
- (a) a D2 receptor agonizing agent or a pharmaceutically acceptable salt thereof;
- (b) a 5HT1A receptor agonizing agent or a pharmaceutically acceptable salt thereof;
- and (c) a pharmaceutically acceptable carrier;
- wherein the foregoing two active agents are present in the composition in amounts such that the combination of such agents in the composition is effective in treating ADHD.
1 more element
A pharmaceutical composition for treating ADHD in a mammal, comprising:
- (a) an α2 adrenergic receptor ligand, or pharmaceutically acceptable salt thereof;
- (b) a D2 receptor agonizing agent, or a pharmaceutically acceptable salt thereof;
- (c) a 5HT1A receptor agonizing agent, or pharmaceutically acceptable salt thereof;
- and (d) a pharmaceutically acceptable carrier;
- wherein the foregoing three active agents are present in the composition in amounts such that the combination of such active agents is effective in treating ADHD.
2 more elements
Dependencies are inferred from the claim text.