Indazoles

Compounds of the general formula (I),

• in which
• Z represents O, S, CH2, CHF or CF2,
• R1 and R2 are identical or different and represent hydrogen, halogen, (C1-C6)-alkyl, CF3, CHF2, CH2F, vinyl or (C3-C7)-cycloalkyl, where at least one of the two substituents is not equal to hydrogen and is in the ortho position relative to the bridge bond,
• R3 represents a group of the formula
• A(CH2)n—(CO)mR8,
• in which
• A represents CH2, O, S, CO or NR9, in which R9 denotes hydrogen, (C1-C6)-alkyl or (C3-C8)-cycloalkyl or represents the group —(CH2)n—(CO)m—O-(C1-C4)-alkyl,
• n represents the numbers 0 to 3,
• m represents the number 0, 1 or 2,
• R8 represents hydrogen, OR10, NR11R12, (C1-C8)-alkyl, (C3-C8)-cycloalkyl, (C6-C10)-aryl, or a saturated, unsaturated or aromatic 5-to 10-membered heterocycle having up to four identical or different heteroatoms from the series S, O and/or N, where the abovementioned radicals are optionally substituted by one, two or three, identical or different substituents from the group halogen, hydroxyl, cyano, nitro, amino, CF3, (C1-C6)-alkyl, (C1-C6)-alkoxy, (C3-C8)-cycloalkyl, —OCO—R13, —CO—O—R14, —CO—NR15R16, —NHCOR17 or NHCOOR17, where R10, R11, R12, R13, R14, R15, R16 and R17 are identical or different and in each case represent hydrogen, phenyl, benzyl, (C1-C6)-alkyl, (C1-C6)-alkoxy or (C3-C8)-cycloalkyl, which for their part are optionally mono- or polysubstituted by halogen, hydroxyl, amino, (C1-C4)-alkoxy, —CO—O(C1-C4)-alkyl, —NH—CO—O(C1-C4)-alkyl, —O—CO—(C1-C4)-alkyl, a heterocycle or optionally halogen- or hydroxyl-substituted phenyl,
• R4 and R5 are identical or different and in each case represent hydrogen, hydroxyl, halogen, cyano, intro, (C1-C4)-alkyl, or the radical of the formula NR18R19, where R18 and R19 have the meaning indicated for R10 and can be identical to or different from this substituent,
• R6 represents halogen or has the meaning indicated for R8 and is identical to or different from this substituent or represents the radical
• in which
• R20 and R21 together represent oxygen, or are each identical or different and represent hydrogen, halogen, hydroxy, (C1-C6)-alkyl, (C1-C6)-alkoxy or the radical —NR15R16 and
• R22 has the meaning of R8 and is identical to or different from this,
• R7 represents hydrogen or an acyl group and their salts.