Remedies for joint diseases
AssigneesTakata Seiyaku Co., Ltd., Richter Gedeon Vegyeszeti Gyar Rt.
InventorsIsao Serizawa, Keisei Maekawa, Janos Illes, Erzsebet Neszmeli
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Abstract
The present invention provides an agent for treatment of arthritic diseases such as rheumatoid arthritis that has for its active ingredient a complex of hyaluronic acid and zinc. This complex synergistically inhibits proliferation of synovial cells and suppresses matrix metalloproteinase MMP-9, which is produced by synovial cells, as compared with its constituents, hyaluronic acid and zinc, alone.
Claims13
A treatment method for arthritic disease comprising administration of a complex of hyaluronic acid and zinc to a patient having an arthritic disease.
A method of suppressing accelerated production of matrix metalloproteinase MMP-9 comprising administration of a complex of hyaluronic acid and zinc to a patient having accelerated production of matrix metalloproteinase MMP-9.
Dependencies are inferred from the claim text.