Human adenylsuccinate synthetase and polynucleotides encoding the same

An isolated nucleic acid molecule comprising a nucleotide sequence that:

• (a) encodes the amino acid sequence shown in SEQ ID NO:
• 2;
• or
• (b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO:
• 1 or the complement thereof wherein, the conditions are hybridization to filter-bound DNA in 0.5 M NaHPO4, 7% sodium dodecyl sulfate (SDS), 1 mM EDTA at 65° C. and washing in 0.1×SSC/0.1% SDS at 68° C., wherein said nucleic acid has at least 85% identity with the nucleotide sequence of SEQ ID NO:
• 1, or the complement thereof, and encodes an adenylsuccinate synthethase.