US 6,607,886 B2 · Method and apparatus for simultaneous quantification of different radionuclides in a large number of regions on the surface of a biological microarray or similar test objects

Abstract

The present invention relates to a method and apparatus for simultaneous quantification of the amounts of one or more radioactive nuclides within arbitrary regions on a surface where these nuclides have been deposited, adsorbed or fixed. These radioactive nuclides serve as markers on compounds that typically have been incorporated into tissue sections or into larger biological molecules that by various mechanisms have been bound to chemical substances on this surface. The method is especially well suited for DNA microarray deductions through the use of nucleotides labelled with different beta-emitting radionuclides.

Claims12

Dependent claims

A method for simultaneous quantification of the amounts of one or more radioactive nuclides within arbitrary regions on a probe surface comprising depositing, adsorbing or fixing one or more radioactive nuclides on a probe surface;

and detecting the radioactive nuclides which serve as markers on compounds that have been incorporated into target tissue sections, target chemical compounds or biological molecules that have been deposited, adsorbed or fixed to chemical or biological probe substances on said probe surface.

Dependencies are inferred from the claim text.

Facts

Application

09/775,515Filed 1 Feb 2001

Published

US 2002/0142301 A13 Oct 2002

Granted

19 Aug 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification4 codes

C12Q 1/6809
Involving nucleic acids: methods for determination or identification of nucleic acids involving differential detection
G16B 25/00
Ict specially adapted for hybridisation
C12Q
Measuring or testing processes involving enzymes, nucleic acids or microorganisms
G16B
Bioinformatics, i.e. information and communication technology [ict] specially adapted for genetic or

Method and apparatus for simultaneous quantification of different radionuclides in a large number of regions on the surface of a biological microarray or similar test objects

Life of this patent

Method and apparatus for simultaneous quantification of different radionuclides in a large number of regions on the surface of a biological microarray or similar test objects

Life of this patent

Abstract

Claims12