Surface antigen
AssigneeThe University of Queensland
InventorsIan Richard Anselm Peak, Michael Paul Jennings, E. Richard Moxon
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Abstract
The invention provides a novel surface polypeptide from Neisseria meningitidis as well as nucleic acid and nucleic acid sequence homologues encoding this protein. Pharmaceutical compositions containing the polypeptide and nucleic acids of the invention are also disclosed as well as methods useful in the treatment, prevention and diagnosis of N. meningitidis infection.
Claims5
An isolated protein which, upon administration to a mammal, elicits an immune response against Neisseria meningitidis, wherein the isolated protein comprises an amino acid sequence as set forth at positions 477 to 497 of SEQ ID NO:2.
A pharmaceutical composition for eliciting an immune response against Neisseria meningitidis comprising (A) at least one protein comprising an amino acid sequence as set forth at positions 477 to 497 of SEQ ID NO:2;
- and (B) a pharmaceutically acceptable carrier.
A method of eliciting an immune response in a subject against Neisseria meningitidis, comprising:
- administering to the subject an isolated protein, wherein the isolated protein comprises an amino acid sequence as set forth at positions 477 to 497 of SEQ ID NO:2.
Dependencies are inferred from the claim text.