Precise administration of a medicated aerosol via the lungs

A device for deposition of a medicament in a liquid form in the lungs, comprising:

• an inhalation mouthpiece;
• a pressure sensor responsive to a suction pressure in said mouthpiece to produce a triggering signal;
• an adjustable vaporiser coupled to the inhalation mouthpiece and to receive a nozzle flow, which vaporizer contains the medicament and issues high frequencies to deliver the vaporised medicament to the mouthpiece for a vaporising period in response to a vaporising signal;
• a compressed-air control valve, which, in response to a valve signal, opens to allow the nozzle flow to enter the vaporiser throughout the vaporising period to provide a predetermined inhaled volume, and closes at the end of the vaporising period to stop the nozzle flow;
• a volumetric flow controller coupled to the compressed-air control valve to preset a determined quantity of a volumetric flow of the nozzle flow;
• a flow meter disposed downstream of said volumetric flow controller for control of a predetermined volumetric flow;
• and
• an electronic controller that receives the triggering signal from the pressure sensor to produce the valve signal and the vaporising signal, said electronic controller being configured with the settable vaporising period and a settable pause interval and controlling the high frequencies issued by the vaporizer and operable to set the varporing period of the adjustable vaporiser to an invariable value from opening of the compressed-air control valve and causes a predetermined volume for each respiratory manoeuvre at the inhalation mouthpiece.

A method for administration of a medicated aerosol via lungs, comprising:

• providing an adjustable vaporiser to vaporize a medication to be delivered through a mouthpiece for inhalation;
• providing a controllable air flow via a compressed-air control valve to the adjustable vaporiser to produce the medicated aerosol and direct the medicated aerosol to the mouthpiece;
• using a volumetric flow controller coupled to the compressed-air control valve to preset a determined quantity of a volumetric flow;
• using a flow meter downstream of the compressed-air control valve to control the air flow at a constant flow rate;
• using a pressure sensor at the mouthpiece to produce a triggering signal upon sensing a suction at the mouthpiece;
• in response to the triggering signal, turning on the adjustable vaporizer to operate and opening the compressed-air control valve to allow the controllable air flow into the adjustable vaporiser, for a predetermined invariable vaporizing period;
• and
• turning off both the adjustable vaporiser and the compressed-air control valve at the end of the vaporizing period to provide a predetermined constant volume of the medication for different respiratory manoeuvres.