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US 6,605,716 B2Granted
Process for the preparation of hydroxy and amino compounds
AssigneeConsortium fuer Elektrochemische Industries, GmbH
InventorsKlaus Sorger, Hermann Petersen
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Abstract
A process for the preparation of hydroxy and amino compounds, in which, in a first step, an aldehyde, ketone or imine is reacted in a Reformatsky reaction with a reactive halogen compound and zinc, in carboxylic esters as solvents, the reactive halogen compound being brought into contact with the zinc at the same time as or after contact with the aldehyde, ketone or imine, and in a second step, the reaction product of the first step is hydrolyzed.
Claims20
A process for the preparation of hydroxy and amino compounds, by means of a Reformatsky reaction, comprising:
- a) reacting an aldehyde, ketone, or imine with an organic halogen compound reactive in a Reformatsky reaction, and zinc metal in carboxylic ester solvent;
- and
- b) hydrolyzing the reaction product of the first step,
- wherein said reactive halogen compound is contacted with zinc metal at the same time as with the aldehyde, ketone, or imine, or after the aldehyde, ketone or imine is contacted with zinc metal.
1 more element
Dependencies are inferred from the claim text.