Galectin-11 polypeptides
AssigneesHuman Genome Sciences, Inc., La Jolla Institute for Allergy and Immunology
InventorsJian Ni, Reiner L. Gentz, Craig A. Rosen, Fu-Tong Liu
Life of this patent
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Abstract
The present invention relates to galectin 11 proteins which are members of the galectin superfamily. In particular, the present invention relates to full-length polypeptides, fragments, and variants of galectin 11.
Claims42
An isolated protein comprising an amino acid sequence selected from the group consisting of:
- (a) amino acid residues 1 to 133 of SEQ ID NO:2;
- and
- (b) amino acid residues 2 to 133 of SEQ ID NO:2.
An isolated protein comprising an amino acid sequence selected from the group consisting of:
- (a) the amino acid sequence of the full length polypeptide encoded by the cDNA in ATCC Deposit No. 209053;
- and
- (b) the amino acid sequence of the full-length polypeptide, excluding the N-terminal methionine residue, encoded by the human cDNA clone contained in ATCC Deposit No. 209053.
An isolated fragment of SEQ ID NO:2 comprising an amino acid sequence of SEQ ID NO:2 selected from the group consisting of:
- (a) amino acid residues 1 to 66 of SEQ ID NO:2;
- (b) amino acid residues 5 to 108 of SEQ ID NO:2;
- (c) amino acid residues 5 to 128 of SEQ ID NO:2;
- (d) amino acid residues 40 to 108 of SEQ ID NO:2;
- (e) amino acid residues 47 to 108 of SEQ ID NO:2;
- (f) amino acid residues 65 to 108 of SEQ ID NO:2;
- (g) amino acid residues 65 to 128 of SEQ ID NO:2;
- (h) amino acid residues 88 to 128 of SEQ ID NO:2;
- (i) amino acid residues 101 to 133 of SEQ ID NO:2;
- (j) amino acid residues 47 to 128 of SEQ ID NO:2;
- (k) at least 30 contiguous amino acid residue of amino acid residues 1 to 133 of SEQ ID NO:2;
- and
- (l) at least 50 contiguous amino acid residues of amino acid residues 1 to 133 of SEQ ID NO:2.
An isolated fragment of the full length polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 209053, wherein said fragment comprises an amino acid sequence of the full length polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 209053 selected from the group consisting of:
- (a) at least 30 contiguous amino acid residues of the full length polypeptide encoded by the human cDNA clone contained in ATCC Deposit No 209053;
- and
- (b) 4t least 50 contiguous amino acid residues of the full length polypeptide encoded by the human cDNA clone contained in ATCC Deposit No. 209053.
Dependencies are inferred from the claim text.