Estrogenic substances combined with cruciferous indole compounds
OwnerMilton Hammerlyinventor
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Abstract
Provided herein are medicinal compositions of matter that comprise an estrogenic medication component and a cruciferous indole component (indole 3-carbinol, diindolylmethane, or any derivative thereof. Through use of the compositions of the invention a heretofore unobserved synergy is observed in the treatment of perimenopause, menopause or any other cause of ovarian failure. The invention also provides procedures for administering the composition to a patient who is afflicted with perimenopause, menopause or any other cause of ovarian failure.
Claims8
A single-dose medicament useful in estrogen replacement therapy comprising a composition comprising:
- a) an estrogenic substance;
- and
- b) a cruciferous indole compound,
- wherein said estrogenic substance is selected from the group consisting of:
- estrogen;
- conjugated estrogens;
- dienestrol;
- estrone;
- esterified estrogens;
- estradiol;
- estriol;
- estropipate;
- and ethinyl estradiol, and wherein the quantity of said cruciferous indole compound component is at least 0.5 milligrams.
A single-dose medicament useful in estrogen replacement therapy comprising a composition comprising:
- a) an estrogenic substance;
- and
- b) a cruciferous indole compound,
- wherein said estrogenic substance is selected from the group consisting of:
- estrogen;
- conjugated estrogens;
- dienestrol;
- estrone;
- esterified estrogens;
- estradiol;
- estriol;
- estropipate;
- and ethinyl estradiol, said estrogenic substance being present in any quantity of between 0.10 milligrams and 50 milligrams, and wherein the quantity said cruciferous indole compound component is selected from the group consisting of:
- indole-3-carbinol and diindolylmethane, and wherein said cruciferous indole compound component is present in any amount of between 0.5 and 300 milligrams.
A single-dose medicament useful in estrogen replacement therapy comprising a composition comprising:
- a) an estrogenic substance;
- and
- b) a cruciferous indole compound,
- wherein said estrogenic substance is selected from the group consisting of:
- estrogen;
- conjugated estrogens;
- dienestrol;
- estrone;
- esterified estrogens;
- estradiol;
- estriol;
- estropipate;
- and ethinyl estradiol, and wherein said estrogenic substance is present in any quantity of between 0.10 milligrams and 50 milligrams, and wherein the quantity of said cruciferous indole compound component is present in an amount of at least 0.5 milligrams.
Dependencies are inferred from the claim text.