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US 6,605,466 B1Granted
Epidermis/dermis equivalents and aged skin equivalents shaped therefrom
AssigneeSociete L'Oreal S.A.
InventorsHervé Pageon, Daniel Asselineau, Pierre Tachon
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Abstract
An aged skin equivalent comprising an epidermis equivalent and an aged dermis equivalent, wherein the aged dermis equivalent comprises glycated collagen. An aged dermis equivalent, the epidermis equivalent obtained and methods of producing the aged skin and/or aged dermis equivalent and/or the epidermis equivalent.
Claims11
An aged dermis equivalent comprising collagen subjected to a glycation process and fibroblasts, wherein the aged dermis equivalent has a level of glycation from 2-30 times that of a control dermis comprising collagen not subjected to the glycation process and fibroblasts.
Dependencies are inferred from the claim text.