Immunogenic determinant for use in the diagnosis of Kaposi's sarcoma
OwnerThomas Friedrich Schulz, Patrick S. Moore +2inventors
InventorsThomas Friedrich Schulz, Patrick S. Moore, Guy R. Simpson, Yuan Chang
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Abstract
The present invention relates to an immunogenic determinant. More particularly, it relates to a protein or a protein fragment for use in the diagnosis of Kaposi's sarcoma or human herpesvirus 8 (KSHV/HHV8) and to a diagnostic kit utilising the protein or protein fragment of the invention. The amino acid sequence of the carboxyterminal end of KSHV orf 65 is given below: Sequence 1: Amino acids 86-170 of KSHV orf 65. ADRVSAASY DAGTFTVPSR PGPASGTTPG GQDSLGVSGS SITTLSSGPH SLSPASDILT TLSSTTETTA PAVADARKPP SGKKK.
Claims5
An isolated immunogenic protein fragment consisting essentially of amino acids having the amino acid sequence ADRVSAASAY DAGTFTVPSR PGPASGTTPG GQDSLGVSGS SITTLSSGPH SLSPASDILT TLSSTTETTA PAVADARKPP SGKKK (Sequence Id. No. 1).
Dependencies are inferred from the claim text.