Delivery of biologically active polypeptides
AssigneesVlaams Interuniversitair Instituut Voor Biotechnologie, Microbial Technics Limited
InventorsLothar Steidler, Erik Remaut, Jeremy Mark Wells, Richard William Falla Le Page
Life of this patent
Estimating the term…
Abstract
Biologically active polypeptides and/or antigens are delivered by administering to a subject a non-invasive or non-pathogenic bacterium which expresses one or more antigens or polypeptides. The non-invasive or non-pathogenic bacterium can be included in delivery systems or pharmaceutical formulations.
Claims30
A method of delivering at least one heterologous biologically active polypeptide to a subject in need of same which comprises administering to the subject a non-invasive or non-pathogenic bacterium which constitutively expresses at least one heterologous biologically active polypeptide to illicit a biological response from the subject.
Dependencies are inferred from the claim text.