Gene coding for the measles virus mutant antigen
AssigneeThe Research Foundation for Microbial Diseases of Osaka University
InventorsShigeharu Ueda, Michiko Watanabe, Hitomi Kawanish
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AssigneeThe Research Foundation for Microbial Diseases of Osaka University
InventorsShigeharu Ueda, Michiko Watanabe, Hitomi Kawanish
Estimating the term…
Disclosed is a measles virus mutant gene coding for a measles virus mutant H protein antigen, wherein said gene coding for a measles virus mutant H protein antigen is at least one member selected from the group consisting of the following genes (a) to (c): (a) a gene coding for an amino acid sequence of SEQ ID NO: 10; (b) a gene coding for an amino acid sequence of SEQ ID NO: 3 or SEQ ID NO: 11; and (c) a gene coding for an amino acid sequence of SEQ ID NO: 4 or SEQ ID NO: 12. By the use of the measles virus mutant gene of the present invention, it has become possible to provide efficiently and economically a gene vaccine which is adapted for an epidemic strain of measles virus, and a diagnostic reagent capable of accurately detecting infections with an epidemic strain of measles virus.
A measles virus mutant gene consisting of a gene coding for a measles virus mutant H protein antigen, wherein said gene coding for a measles virus mutant H protein antigen is at least one member selected from the group consisting of the following genes (a) to (c):
A recombinant measles virus mutant gene coding for a recombinant measles virus mutant antigen which is obtained by replacing a part of the H protein of CAM-70 strain shown in SEQ ID NO:
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