Back to results
US 6,605,279 B2Granted
Therapeutic compositions for inhibiting the interactions of B7-1 and B7-2 with their natural ligands
AssigneesGenetics Institute, Inc., Dana-Farber Cancer Institute, Inc.
InventorsGordon J. Freeman, Lee M. Nadler, Gary S. Gray
Life of this patent
Estimating the term…
Abstract
Disclosed is a composition for inhibiting the interactions of B7-1 and B7-2 with their natural ligands. Such compositions comprise an antibody specific for B7-2 and an antibody specific for B7-1, in a pharmaceutically acceptable carrier. The composition may be formulated for either separate or combined administration of the antibody components. The antibodies may be monoclonal antibodies, or humanized antibodies. Preferred antibodies are disclosed.
Claims6
A composition comprising the following components:
- an antibody that recognizes B7-2 (SEQ ID NO:2) and an antibody that recognizes B7-1 (SEQ ID NO:29), wherein each of the components is in a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.