US 6,605,223 B2 · Blood component preparation (BCP) device and method of use thereof

Abstract

An automated blood separation method and apparatus is described that allows for the separation of multiple units of blood simultaneously. The method and apparatus reliably and quickly separates blood into its components. An auto-balancing feature within the apparatus automatically preferably compensates for the changing state of imbalance, thereby eliminating the need for additional balancing steps during the separation process. The apparatus has a rotor into which a plurality of cassettes can be inserted. The cassettes have a number of sections for the containment of the whole blood and for the separated blood components, which are contained in disposable bags. The rotor is placed into a centrifuge assembly, and the blood components are then separated and transferred to the bags in the individual sections of the cassettes. Means for including secondary separation devices such as filters is included. The manufacturing information regarding the lot identities used and the conditions under which each unit was processed is also included.

Claims40

Dependent claims

An automated device for separating blood into its components comprising:

one or more cassettes;
a plurality of cavities in each cassette for housing a whole blood bag and at least one blood component bag;
the whole blood bag and blood component bags in fluid communication with eachother;
wherein the one or more cassettes are stacked in a co-axial configuration in the centrifuge;
wherein the one or more cassettes are placed into a centrifuge and, as the centrifuge spins the one or more cassettes, whole blood in the whole blood bag separates into its components, and the components are caused to flow into different blood component bags.

2 more elements

A method for the separation of whole blood into its components, the method comprising the steps of:

(a) providing an automated device for separating blood into its components comprising:
one or more cassettes;
a plurality of cavities in each cassette for housing at least a whole blood bag and at least one blood component bag;
the whole blood bag and blood component bags in fluid communication with each other;
(b) placing a whole blood bag holding whole blood and at least one blood component bag in the plurality of cavities in each cassette;
(c) placing the one or more cassettes into a centrifuge;
(d) spinning the centrifuge;
(e) allowing the red blood cells to separate from the plasma in the whole blood bag;
(f) allowing the plasma to flow from the whole blood bag to a first blood component bag;
(g) allowing the platelets to sediment radially and collect on the surfaces of the first blood component bag;
and
(h) allowing the plasma minus the platelets collected on the surfaces of the first blood component bag to flow through the first blood component bag into a second blood component bag.

9 more elements

Dependencies are inferred from the claim text.

Blood component preparation (BCP) device and method of use thereof

Life of this patent

Blood component preparation (BCP) device and method of use thereof

Life of this patent

Abstract

Claims40